Skip to Content

EA9131: Leukemia: Acute Promyelocytic Leukemia, Registry

A Simplified Patient Care Strategy to Decrease Early Deaths in Acute Promyelocytic Leukemia (APL)

Objective

Overview

This clinical trial studies how well-simplified patient care strategy works in decreasing early death in patients with acute promyelocytic leukemia. Implementing simplified acute promyelocytic leukemia guidelines along with support from acute promyelocytic leukemia experts may decrease deaths and improve survival.

Key Inclusion Criteria

For a patient to be eligible for participation in this study, all of the following criteria must apply.
  • Confirmed to have a diagnosis of APL, which is defined as:

    • Positive t(15:17) by fluorescence in situ hybridization (FISH) or conventional karyotype
    • Positive promyelocytic leukemia/retinoic acid receptor PML/RAR alpha by polymerase chain reaction (PCR)
  • Patients must accept treatment and supportive care guidelines
  • Referrals must be made as early as possible but no later than 5 calendar days after ATRA therapy is initiated; consent can be obtained up till day 7 or earlier
  • Co-management can be started as soon as referral is made including weekends; the physician at the outlying facility should make every effort to call the APL expert at the first suspicion of APL

Phase: N/A

Learn More

ClinicalTrials.Gov

IRB Protocol Number
EA9131
Principal Investigator(s)
Asim Pati, M.D

Clinical Trial Categories

  • Hematologic Cancer
Sponsor(s)
ECOG-ACRIN Cancer Research Group
How to Participate

Tom Leuck, RN

864-560-1980

tleuck@gibbscc.org

Was this page helpful?

Yes
No

Thank you for your feedback!

Thank you for your feedback and helping us to improve our website.
There will be no additional response.

Upcoming Events

News & Highlights

Stay Connected!

Get the latest news on the health topics that matter most to you.

Sign up