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Published on January 31, 2018

Creatinine Clearance 

SIM

10940 

CPT

82575 

Synonyms

Creat Cl 

Specimen Type

Voided 24 hour Urine and Plasma or Serum 

Container

URINE:  24 hour urine container
BLOOD COLLECTION:  (Blood may be collected at anytime during the 24 hour urine collection period.):
3.5 ml Green - Lithium heparin plasma separator
4.0 ml Gold-top serum separator

Collection Instructions

URINE COLLECTION:
•  Collect all urine voided for 24 hours and place in the 24 hour urine container.
•  No preservative needed.
•  The collection container is to be kept in the refrigerator or on ice during the timed period.
•  Note the number of hours of urine collection on the aliquot.

Volume

URINE:    Max: 5 ml preferred
              Min:  1 ml
BLOOD:  2 ml plasma or serum
             Min: 0.5 ml

Additional Information

none

Patient Preparation

none

Specimen Processing Instructions

URINE: 
Refrigerate, Note the number of hours of urine collection on the aliquot.


BLOOD:

Plasma:  Centrifuge at 3380 rpm’s (±100) for a minimum of 10 minutes

Serum:  Allow to clot.  Centrifuge at 3380 rpm’s (±100) for a minimum of 10 minutes

Centrifuge within 2 hours of collection.

Transport Requirements

Refrigerated

Specimen Stability

URINE:    Refrigerated 5 days;  BLOOD:  Refrigerated  5 days 

Rejection Criteria

Insufficient volume

Reference Range

·         Serum (plasma) = 0.47 – 1.35 mg/dl

·         Urine Creatinine/24 hr = 800 – 1800 mg/24 hr

·         Creatine Clearance     males = 90-139 ml/min

                                              females = 80-125 ml/min

Critical Value

none 

Test Includes

Urine Creatinine, Serum Creatinine, Calculated eGFR 

Methodology

Jaffe rate method 

Testing Frequency

Daily, Monday - Sunday 

 

Reviewed By

Sandy Hammett 

Reviewed Date

1-31-18

Supplemental

  

Reviewed by Sandy Hammett on January 31, 2018

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