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Renin Plasma *

SIM

12200 

CPT

84244 

Synonyms

Plasma Renin Activity; PRA; Renin  

Specimen Type

Plasma 

Container

Lavender-top (EDTA) tube

Collection Instructions

It is recommended that the patient be ambulatory for at least 30 minutes before blood collection.

Volume

Volume: 1 mL 
Min. volume: 0.8 mL(This volume does not allow for repeat testing) 

Additional Information

Measurement of renin activity is useful in the differential diagnosis of individuals with hypertension. This test is not the same as Renin,Direct

Patient Preparation

The patient should be taken off medications for at least three weeks prior to sample collection.  Dietary sodium levels during the period prior to testing can affect renin levels. Patient should be ambulatory for 30 minutes before collection.

Specimen Processing Instructions

Specimen should be at room temperature before centrifugation. After centrifugation transfer specimen and freeze immediately.

Transport Requirements

Frozen

Specimen Stability

 Frozen :14 days 

Rejection Criteria

Gross hemolysis; serum or heparinized plasma; specimen not frozen.

Reference Range

Reference range accompanies report

Critical Value

 

Test Includes

Renin activity 

Methodology

The renin in plasma is allowed to act on the plasma's endogenous substrate, angiotensinogen producing angiotensin I. This is measured by liquid chromatography/mass spectrometry (LC/MS-MS). 

Testing Frequency

 

LCA

002006 

Reviewed By

  Lisa McBride               

Reviewed Date

2/20/2018

Supplemental

* Denotes Reference Lab Test

Reviewed by Lisa McBride on February 20, 2018

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