Lab Test Details
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SIM |
LAB2901 |
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85303 |
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Protein C Functional; Protein C Activity |
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Plasma, frozen |
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Blue-top (sodium citrate) tube |
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Blood should be collected in a blue-top tube containing 3.2 % buffered sodium citrate. Evacuated collection tubes must be filled to completion to ensure a proper blood to anticoagulant ratio. The sample should be mixed immediately by gentle inversion at least six times to ensure adequate mixing. Do not draw from an arm with a heparin lock or heparinized catheter. |
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Volume: 1 mL |
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Confirmation and characterization of protein C deficiency |
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Ideally, the patient should not be on anticoagulant therapy. Avoid warfarin (Coumadin®) therapy for two weeks prior to the test and heparin, direct Xa, and thrombin inhibitor therapies for about three days prior to testing. Do not draw from an arm with a heparin lock or heparinized catheter. |
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Once in the lab, separate plasma from cells as soon as possible. |
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Frozen |
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Frozen : 7 days |
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Severe hemolysis; improper labeling; clotted specimen; specimen diluted with IV fluids; samples thawed in transit; improper sample type; sample out of stability |
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Reference range accompanies report |
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Protein C |
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Protein C in plasma is activated by a specific enzyme (protein C activator) from copperhead snake venom (Agkistrodon contortrix). The amount of activated protein C is determined. The resulting activated PC (Protein Ca) is determined as the rate of hydrolysis of a chromogenic substrate in a kinetic test by measuring the increase in absorbance at 405 nm. |
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117705 |
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Rhonda Crowe |
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2/27/23 |
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* Denotes Reference Lab Test |