Lab Test Details
|
SIM |
LAB532 |
|
CPT |
84244 |
|
Synonyms |
Plasma Renin Activity; PRA; Renin |
|
Specimen Type |
Plasma, frozen |
|
Container |
Lavender-top (EDTA) tube |
|
Collection Instructions |
It is recommended that the patient be ambulatory for at least 30 minutes before blood collection. |
|
Volume |
Volume: 1 mL |
|
Additional Information |
Measurement of renin activity is useful in the differential diagnosis of individuals with hypertension. This test is not the same as Renin, Direct |
|
Patient Preparation |
The patient should be taken off medications for at least three weeks prior to sample collection. Dietary sodium levels during the period prior to testing can affect renin levels. Patient should be ambulatory for 30 minutes before collection. |
|
Specimen Processing Instructions |
Draw blood into an EDTA tube. Keep tube at room temperature. Centrifuge at room temperature. |
|
Transport Requirements |
Frozen |
|
Specimen Stability |
Frozen : 14 days |
|
Rejection Criteria |
Gross hemolysis; serum or heparinized plasma; specimen not frozen. |
|
Reference Range |
Reference range accompanies report |
|
Critical Value |
|
|
Test Includes |
Renin activity |
|
Methodology |
The renin in plasma is allowed to act on the plasma's endogenous substrate, angiotensinogen producing angiotensin I. This is measured by liquid chromatography/mass spectrometry (LC/MS-MS). |
|
Testing Frequency |
|
|
LCA |
002006 |
|
Reviewed By |
Rhonda Crowe |
|
Reviewed Date |
2/27/23 |
|
Supplemental |
* Denotes Reference Lab Test |