SNP Microarray POC*

SIM

LAB3205

CPT

81229 

Synonyms

Reveal SNP Microarray-Products of Conception/Tissue; SNP Array; CGH; 

Specimen Type

Preferred nonfixed tissue or products of conception (POC)/placental villus biopsy

Container

Sterile container containing sterile Ringer's lactate or Hanks' balanced salt solution or transport medium provided by the cytogenetics laboratory. (Do not use isotonic saline as a transport medium or urine containers for shipping.)

Kits are available in Labor and Delivery or the main laboratory of the hospital.

Collection Instructions

Aseptically obtain a small piece of fetal tissue that does not appear necrotic. If specimen is POC, placental villi or membranes may be the only fetal derived tissue available and an effort should be made to submit these tissues rather than maternal decidua. 
Kits must be used for collection. Questionnaire and signed consent form must be filled out completely before delivering specimens to the laboratory for transport to lab Corp. 

Volume

>8 mg tissue

Additional Information

Detects chromosomal imbalance that may be associated with fetal loss and is ideal for detection of complete or partial moles. 
Patients that have had multiple miscarriages may be a candidate for this assay. 
This assay does not detect balanced rearrangements, low-level mosaicism or tetraploidy.

Patient Preparation

Patient must sign consent form.

Specimen Processing Instructions

Kit must be used for collection of specimen. Completed questionnaire along with signed consent form must accompany specimen to the laboratory.

Test must be ordered in LIS.

Transport Requirements

Room temperature

Specimen Stability

Rejection Criteria

1.Specimens  in isotonic saline or formalin are UNACCEPTABLE. 
2.Necrotic tissue 
3.QNS 
4.Frozen specimens 
5.Specimens received in box contaminated with blood or body fluids.

Reference Range

Reference Range accompanies report

Critical Value

Test Includes

Methodology

Whole genome SNP based copy number microarray analysis targeting 2.695 million copy number and allele-specific genome sites. 

Testing Frequency

LCA

510110 

Reviewed By

Rhonda Crowe

Reviewed Date

Supplemental

* Denotes Reference Lab Test