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Oncology
Hematologic Cancer
- Myelodysplastic Syndromes & Acute Myeloid Leukemia, (Connect® MDS/AML) Observational
- A Study Comparing Daratumumab, VELCADE (Bortezomib), Lenalidomide, and Dexamethasone (D-VRd) With VELCADE, Lenalidomide, and Dexamethasone (VRd) in Participants With Untreated Multiple Myeloma and for Whom Hematopoietic Stem Cell Transplant is Not PlannedAccepting Participants
- Immunotherapy (Nivolumab or Brentuximab Vedotin) Plus Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III-IV Classic Hodgkin Lymphoma (S1826)Accepting Participants
- Leukemia, Acute Promyelocytic (EA9131) ObservationalAccepting Participants
- Leukemia, Chronic Lymphocytic (CLL), Untreated Older Patients (A041702)Accepting Participants
- Leukemia, Chronic Lymphocytic (CLL), Untreated Younger Patients (EA9161)Accepting Participants
- Leukemia, Chronic Myeloid (S1712)Accepting Participants
- Multiple Myeloma, Refractory to Lenalidomide (A061202)Accepting Participants
- Myelodysplastic Syndromes & Acute Myeloid Leukemia, (Connect® MDS/AML) ObservationalAccepting Participants
- Randomized Phase II Trial in Early Relapsing or Refractory Follicular Lymphoma (S1608)Accepting Participants
- Blood Sample Collection to Evaluate Biomarkers in Subjects With Untreated Hematologic Malignancies (2018-02)In Progress
- Leukemia, Acute Lymphocytic (ALL), Adolescent & Young Adult (ACCL16N1CD)In Progress
- Leukemia, Chronic Lymphocytic (PCYC-1134M), RegistryIn Progress
- Lymphoma, Diffuse Large B-Cell, Relapsed or Refractory (1562-201)In Progress
- Lymphoma, Diffuse Large B-Cell, Treatment Naïve (DB102-02)In Progress
- Lymphoma, Hodgkin (CA209655) ObservationalIn Progress
- Lymphoma, Mantle Cell, Previously Treated (AFT-32)In Progress
- Multiple Myeloma, Untreated, Stem Cell Transplant Not Planned (54767414MMY3019)In Progress
- Multiple Myeloma: 1st Line Therapy (E1A11)In Progress
- Myelodysplastic Syndromes (MDS) (NHLBI-MDS) ObservationalIn Progress
- Myelofibrosis or Essential Thrombocythemia (INCB-MA-MF-401) RegistryIn Progress
- A Randomized Study of Daratumumab Plus Lenalidomide Versus Lenalidomide Alone as Maintenance Treatment in Patients With Newly Diagnosed Multiple Myeloma Who Are Minimal Residual Disease Positive After Frontline Autologous Stem Cell Transplant (MMY3021)Closed
- Plasmacytoma of the Bone (A061402)Complete
Symptom Management & Cancer Control
- All Disease Sites; Health Disparities (DCP-001)Accepting Participants
- Breast Cancer Survivors, Cognitive Impairment, (REMEMBER) (WF 97116)Accepting Participants
- Randomized Placebo Controlled Trial of Bupropion For Cancer Related Fatigue (URCC 18007)Accepting Participants
- Screening Mammogram (TMIST) (EA1151)Accepting Participants
- Survivors, Work Ability in Young Adult Survivors (WF 10217)Accepting Participants
- Treatment Effects on Development of Chemotherapy-Induced Peripheral Neuropathy in Patients With Cancer (S1714)Accepting Participants
- Weight Loss - Breast Cancer (A011401) (BWEL)Accepting Participants
- Breast Cancer, Young Women, Pregnancy Outcomes (POSITIVE) (A221405)In Progress
- Breast or Gynecologic Cancer, Improving Sexual Desire (NRG-CC004)In Progress
- Head and Neck, Squamous Cell Carcinoma, Oral Mucositis (IDR-OM-02)In Progress
- Lung Cancer, Survivors (RELAX) (WF01213)In Progress
- Non-small Cell Lung Cancer NSCLC; Stages I-II; African-American, (WF01414) ObservationIn Progress
- Stage I-II Breast Cancer, MRI and Mammography Before Surgery (A011104)In Progress
- Colorectal Cancer, Cognitive Impairment (URCC 16092)Complete
- Ovarian, Fallopian Tube, and Primary Peritoneal, Diet & Physical Activity (GOG-0225)Complete
Gastrointestinal Cancer
- Blood and Stool Sample Collection in Subjects With a Diagnosis of Colorectal Cancer or Colorectal Lesion: Act Fast (EA2018-07)Accepting Participants
- Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair, (A021502)Accepting Participants
- Nivolumab After Combined Modality Therapy in Treating Patients With High Risk Stage II-IIIB Anal Cancer (EA2165)Accepting Participants
- Phase II/III Study of Circulating Tumor DNA as a Predictive Biomarker in Adjuvant Chemotherapy in Patients with Stage IIA Colon Cancer (COBRA)(NRG GI005)Accepting Participants
- Vitamin D3 With Chemotherapy and Bevacizumab in Treating Patients With Advanced or Metastatic Colorectal Cancer, SOLARIS (A021703)Accepting Participants
- Advanced Cancer, ALT-803 in Combination With PD-1/PD-L1 Checkpoint Inhibitor (QUILT-3.055)In Progress
- Advanced Solid Tumors w/ FGF/FGFR Aberrations (TPU-TAS-120-101)In Progress
- Colon or Rectal Cancer, Stage I-III, Financial Burden Assessment (EAQ162CD)In Progress
- Combination Chemotherapy, Bevacizumab, and/or Atezolizumab in Treating Patients With Deficient DNA Mismatch Repair Metastatic Colorectal Cancer (NRG GI004)In Progress
- Liver, Non-resectable, (RESIN) RegistryIn Progress
- Solid Tumors, Blood Sample Collection to Evaluate Biomarkers (2018-01)In Progress
- Cholangiocarcinoma, Nonresectable or Metastatic IDH1 Mutation (AG120-C-005)Complete
- Colorectal Cancer, Cognitive Impairment (URCC 16092)Complete
- Pancreatic Adenocarcinoma, Metastatic (ABI-007-PANC009)Complete
- Pancreatic Adenocarcinoma, Metastatic (NLG2104)Complete
- Pancreatic Cancer, Metastatic (RX-3117)Complete
Cutaneous & Sarcoma Cancer
Breast Cancer
- Breast Cancer Survivors, Cognitive Impairment, (REMEMBER) (WF 97116)Accepting Participants
- Post Mastectomy Radiation w/Breast Reconstruction (A221505)Accepting Participants
- Post-Mastectomy and Post-Lumpectomy; Positive Axillary Nodes (NSABP B-51)Accepting Participants
- Randomized Placebo Controlled Trial of Bupropion For Cancer Related Fatigue (URCC 18007)Accepting Participants
- Screening Mammogram (TMIST) (EA1151)Accepting Participants
- Triple Receptor-Negative Breast Cancer (S1418/BR006)Accepting Participants
- Triple-Negative Basal-Like Breast Cancer (EA1131)Accepting Participants
- Triple-Negative, Node-Positive or High-Risk Node-Negative (NRG-BR003)Accepting Participants
- Weight Loss - Breast Cancer (A011401) (BWEL)Accepting Participants
- A Phase IIR/III Trial of Standard of Care Therapy With or Without Stereotactic Body Radiotherapy (SBRT) and/or Surgical Ablation for Newly Oligometastatic Breast CancerIn Progress
- A Randomized, Double-Blind, Phase III Clinical Trial of Neoadjuvant Chemotherapy With Atezolizumab or Placebo in Patients With Triple-Negative Breast Cancer Followed by Adjuvant Continuation of Atezolizumab or Placebo (NSABP B-59)In Progress
- Advanced Breast Cancer (A5481082) ObservationalIn Progress
- Breast Cancer, Young Women, Pregnancy Outcomes (POSITIVE) (A221405)In Progress
- Breast or Gynecologic Cancer, Improving Sexual Desire (NRG-CC004)In Progress
- HER2 Negative Primary Breast Cancer, gBRCA1/2 Mutations and High Risk (NSABP B-55)In Progress
- HER2- Positive Breast Cancer, Brain Metastasis (RTOG 1119)In Progress
- High Risk, Node-Positive, Early Stage (NSABP B-58)In Progress
- High-Risk; Hormone Receptor-Positive and HER2/Neu Negative (S1207)In Progress
- Solid Tumors, Blood Sample Collection to Evaluate Biomarkers (2018-01)In Progress
- Stage I-II Breast Cancer, MRI and Mammography Before Surgery (A011104)In Progress
- Triple Negative Breast Cancer (RX-5902)Complete
Cancer Care Delivery Research (CCDR)
Thoracic Cancer
- Effects of Intravenous GC4419 on the Incidence and Severity of Esophagitis Due to Chemoradiotherapy for Lung CancerAccepting Participants
- Limited Stage Small Cell Lung Cancer (LS-SCLC): A Phase II/III Randomized Study of Chemoradiation Versus Chemoradiation Plus Atezolizumab (NRG LU-005)Accepting Participants
- Non-small Cell Lung Cancer (NSCLC), Metastatic (NRG LU-002)Accepting Participants
- Non-small Cell Lung Cancer ALCHEMIST (A151216)Accepting Participants
- Non-small Cell Lung Cancer, Early Stage, Resected, Harboring ALK (E4512)Accepting Participants
- Ramucirumab and Pembrolizumab Versus Standard of Care in Treating Patients With Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Non-Match Treatment Trial) (S1800A)Accepting Participants
- Rucaparib in Treating Patients With Genomic LOH High and/or Deleterious BRCA1/2 Mutation Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial) (S1900A)Accepting Participants
- Testing the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung Cancer (EA5163/ S1709)Accepting Participants
- Adenoma and Second Primary Prevention Trial (S0820)In Progress
- Advanced Cancer, ALT-803 in Combination With PD-1/PD-L1 Checkpoint Inhibitor (QUILT-3.055)In Progress
- Lung Cancer, Survivors (RELAX) (WF01213)In Progress
- LUNGMAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung Cancer, (Screening Study)In Progress
- Non-small Cell Lung Cancer NSCLC, EGFR Mutant (A081105)In Progress
- Non-small Cell Lung Cancer NSCLC; Stages I-II; African-American, (WF01414) ObservationIn Progress
- Non-small Cell Lung Cancer, Previously Treated (SWOG LungMAP)In Progress
- Phase III Comparison of Thoracic Radiotherapy Regimens in Patients With Limited Small Cell Lung Cancer Also Receiving Cisplatin and Etoposide (CALGB-30610)In Progress
- Small Cell Lung Cancer, Relapsed or Refractory, Second-Line (DIV-SCLC-301)In Progress
- Solid Tumors, Blood Sample Collection to Evaluate Biomarkers (2018-01)In Progress
Precision Medicine & Rare Tumors
- Germ Cell Tumor, Pediatric and Adult Patients (COG AGCT1531)Accepting Participants
- Leukemia, Chronic Myeloid (S1712)Accepting Participants
- Merkel Cell Carcinoma, Resected (EA6174)Accepting Participants
- Non-small Cell Lung Cancer ALCHEMIST (A151216)Accepting Participants
- Solid Tumors or Lymphomas; MATCH (EAY131)Accepting Participants
- Solid Tumors, Rare Tumor Types, DART (S1609)Accepting Participants
- Advanced Cancer, ALT-803 in Combination With PD-1/PD-L1 Checkpoint Inhibitor (QUILT-3.055)In Progress
- Advanced Solid Tumors w/ FGF/FGFR Aberrations (TPU-TAS-120-101)In Progress
- HER2 Negative Primary Breast Cancer, gBRCA1/2 Mutations and High Risk (NSABP B-55)In Progress
- Lymphoma, Diffuse Large B-Cell, Treatment Naïve (DB102-02)In Progress
- Lymphoma, Hodgkin (CA209655) ObservationalIn Progress
- Lymphoma, Mantle Cell, Previously Treated (AFT-32)In Progress
- Melanoma, Stage III-IV BRAF Mutant (S1320)In Progress
- Merkel Cell Carcinoma, Advanced (A091605)In Progress
- Non-small Cell Lung Cancer NSCLC, EGFR Mutant (A081105)In Progress
- Solid and Liquid Tumors: Newly Diagnosed With No Treatment Started (GRAIL-001) ObservationIn Progress
- Solid Tumors (eFT508-0010)In Progress
Other
Wound Healing - Infectious Disease
